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Ciracle Anti Wrinkle Drama Peptide Cream

30ml / 1.0 fl.oz.

Description

* Skin Permeable Biological Active Peptides make Anti-Wrinkle
* Botox Peptide Cream (BTX Cream)

Peptide moisturizing cream with a texture that is effective in improving fine wrinkles caused by repeated smiles or repeated facial expressions, and wrinkles on the face and neck caused by external environmental stress. In particular, it is effective in moisturizing and anti-wrinkle around your eyes.

Key Ingredients

Acetyl Hexapeptide-8, Palmitoyl Tripeptide-1, Copper Tripeptide-1,
Adenisine, Squalan, Sodium Hyaluronate, Tocopheryl acetate

Skin Concerns

  • Cream / Lotion

Category

  • Anti-aging
  • All Products

Skin Type

  • Normal Skin

We developed this item by the formulation research of a moist and creamy texture that is suitable to use to promote skin absorption of peptide complexes, moisturizing ingredients, and plant-derived active ingredients.

 

 

 

 

 

Acetyl Hexapeptide-8


  Commonly referred to as ‘Botox in a jar’, it is a peptide compound used to reduce the appearance of fine lines caused by repeated facial expressions, such as crow’s feet, glabellar lines or nasolabial lines.


  Due to its similar structure to botulinum toxin, acetyl hexapeptide 8 in considered an excellent, non-invasive alternative to Botox (1). It promotes the skin’s natural production of type 1 collagen, the crucial protein which forms large, eosinophilic fibers to rebuild muscles, reducing fine lines and wrinkles. This ingredient blocks signals from the nerves to the muscles, these muscles can no longer retract, causing the wrinkles to relax and soften.

  It also optimizes collagen function, which, along with the skin-smoothing effects, improves moisture levels in the skin (2). 

  Research shows that it can reduce wrinkle depth by up to 30% when used for 30 consecutive days (3) (Figure 1).

 

 

 

 

Palmitoyl Tripeptide-1


  Palmitoyl tripeptide-1, also called pal-GHK and palmitoyl oligopeptide (Sequence: Pal-Gly-His-Lys), is a messenger peptide for collagen renewal.

  Comparable to retinoic acid with regards to its activity, it does not trigger irritation. Collagen and glycosaminoglycan synthesis are stimulated, the epidermis is reinforced, and wrinkles are diminished (2) .

  It is used in cosmetic anti-wrinkle skincare and make-up products. In a study with 15 women, a cream containing palmitoyl tripeptide-1 was applied twice daily for four weeks, leading to statistically significant reductions in wrinkle length, depth and skin roughness (4).

 

 

Copper Tripeptide-1


  Several copper(II)-peptide complexes occur naturally. In human plasma, the level of GHK-Cu is about 200 ng/ml at age 20. By the age of 60, the level drops to 80 ng/ml.

  In humans, GHK-Cu is proposed to promote wound healing, attraction of immune cells, antioxidant and anti-inflammatory effects, stimulation of collagen and glycosaminoglycan synthesis in skin fibroblasts and promotion of blood vessels growth.

  Other studies revealed its ability to modulate expression of a large number of human genes, generally reversing gene expression to a healthier state. Synthetic GHK-Cu is used in cosmetics as a reparative and anti-aging ingredient (5,6) (Figure 2).

 

 

 

 

 

 

 

 

1. Lim, S.H., et al. Enhanced Skin Permeation of Anti-wrinkle Peptides via Molecular Modification. Sci Rep 2018: 8, 1596

2. Schagen S. K. Topical Peptide Treatments with Effective Anti-Aging Results. Cosmetics 2017;4(2):16 (doi.org/10.3390/cosmetics4020016)

3. Blanes-Mira, C., et al. A synthetic hexapeptide (Argireline) with antiwrinkle activity. Int. J. Cosmet. Sci. 2002;24:303–310

4. Lintner, K.; Peschard, O. Biologically active peptides: From a laboratory bench curiosity to a functional skin care product. Int. J. Cosmet. Sci. 2000;(22), 207–218

5. Pickart L. The human tri-peptide GHK and tissue remodeling. J Biomater Sci Polym Ed. 2008;19(8):969-88

6. Peter Elsner, et al. Cosmeceuticals and active cosmetics. Drug versus Cosmetics. 2nd Edition. 2005. p.550-561

KEY Ingredients

Acetyl Hexapeptide-8, Palmitoyl Tripeptide-1, Copper Tripeptide-1
Adenisine, Squalan, Sodium Hyaluronate, Tocopheryl acetate


FULL Ingredients

Water, Butylene Glycol, Squalane, Simmondsia Chinensis (Jojoba) Seed Oil, Dimethicone, C14-22 Alcohols, 1,2-Hexanediol, Phenyl Trimethicone, Glycerin, Arachidyl Alcohol, Polyacrylate-13, Cetearyl Olivate, Methyl Glucose Sesquistearate, Hydrogenated Lecithin, Behenyl Alcohol, Sorbitan Olivate, C12-20 Alkyl Glucoside, Tocopheryl Acetate, Glycine Soja (Soybean) Sterols, Caffeine, Polyisobutene, Arachidyl Glucoside, Caprylic/Capric Triglyceride, Caprylyl Glycol, Xanthan Gum, Scutellaria Baicalensis Root Extract, Ethylhexylglycerin, Polysorbate 20, Panthenol, Hydrolyzed Collagen, Glyceryl Polyacrylate, Allantoin, Sorbitan Isostearate, Adenosine, Carthamus Tinctorius (Safflower) Flower Extract, Citrus Aurantium Dulcis (Orange) Peel Oil, Phenoxyethanol, Sodium Hyaluronate, Acetyl Hexapeptide-8, Palmitoyl Tripeptide-1, PEG-40 Hydrogenated Castor Oil, PPG-26-Buteth-26, Copper Tripeptide-1, Limonene

 Apply to the face, neck, and décolletage after cleansing and toning. It is recommended to use it as an eye cream around the eyes.

 

 Recommended using with CIRACLE vitamin source C-20.